Jean-François Toussaint, madaxa Sanofi Pasteur ee cilmi baarista caalamiga ah iyo horumarinta, ayaa ka digay in guusha tallaalada mRNA ee ka dhanka ah Covid aysan dammaanad qaadin natiijooyin la mid ah hargabka.
"Waxaan u baahanahay inaan is-hoosaysiino," ayuu yidhi."Xogta ayaa noo sheegi doonta haddii ay shaqeyso."
Laakiin daraasaadka qaarkood waxay soo jeedinayaan in tallaalada mRNA laga yaabo inay caddeeyaan inay ka awood badan yihiin kuwa dhaqanka.Daraasadaha xayawaanka, tallaallada mRNA waxay u muuqdaan inay bixiyaan difaac ballaaran oo ka dhan ah fayraska hargabka.Waxay ku dadajiyaan habka difaaca xayawaanka inay sameeyaan unugyada difaaca jirka ee ka hortagga fayraska, waxayna sidoo kale tababaraan unugyada difaaca si ay u weeraraan unugyada cudurka qaba.
Laakin malaha ugu muhimsan hargabka, tallaalada mRNA si degdeg ah ayaa loo samayn karaa.Xawaaraha wax soo saarka mRNA wuxuu u oggolaan karaa kuwa tallaalka sameeyay inay sugaan dhowr bilood oo dheeri ah ka hor inta aysan dooran noocyada hargabka si ay u isticmaalaan, taasoo u horseedi karta ciyaar wanaagsan.
"Haddii aad dammaanad qaadi karto 80 boqolkiiba sannad kasta, waxaan u maleynayaa inay taasi noqon doonto faa'iido weyn oo caafimaadka dadweynaha," ayuu yiri Dr. Philip Dormitzer, sarkaalka madaxa sayniska ee Pfizer.
Farsamada ayaa sidoo kale u fududaynaysa kuwa sameeya tallaalka mRNA inay abuuraan tallaalo isku dhafan.Marka ay la socdaan molecules mRNA ee noocyada kala duwan ee hargabka, waxay sidoo kale ku dari karaan molecules mRNA ee cudurada neef-mareenka oo dhan.
Bandhigga Sebtembar 9 ee maalgashadayaasha, Moderna waxay la wadaagtay natiijooyinka tijaabo cusub oo ay cilmi-baarayaashu siiyeen tallaallo jiirar ah oo isku daraya mRNA-yada saddexda fayras ee neef-mareenka: ifilada xilliyeed, Covid-19 iyo cudur-sidaha caadiga ah ee loo yaqaanno fayraska syncytial breath, ama RSV.Jiirarku waxay soo saareen heerar sare oo ka hortag ah dhammaan saddexda fayras.
Cilmi-baarayaal kale ayaa raadinaya tallaal caalami ah oo dadka ka ilaalin kara sannado badan iyagoo iska ilaalinaya noocyo badan oo hargab ah.Halkii la tallaali lahaa sannadlaha ah, dadku waxay u baahnaan karaan uun xooji dhowrkii sannadoodba mar.Xaaladda ugu fiican, hal talaal ayaa laga yaabaa inuu shaqeeyo inta uu nool yahay.
Jaamacadda Pennsylvania, koox cilmi-baarayaal ah oo uu hoggaaminayo Norbert Pardi ayaa soo saaraya tallaallo mRNA ah kuwaas oo soo koobaya borotiinnada fayraska hargabka kuwaas oo si dhif ah isu beddela.Tijaabooyin lagu sameeyay xayawaanka ayaa tilmaamaya in tallaaladani ay sii jiri karaan waxtar sanadba sanadka ka dambeeya.
Inkasta oo Moderna aanu hadda ka shaqaynayn tallaalka ifilada caalamiga ah, "dhab ahaantii waa wax aan xiisayneyno mustaqbalka," ayuu yiri Dr. Jacqueline Miller, madaxa shirkadda cilmi-baarista cudurrada faafa.
Xitaa haddii tallaalada hargabka mRNA ay ku noolaadaan wixii laga filayey, waxay u badan tahay inay u baahan doonaan dhowr sano si ay u helaan oggolaansho.Tijaabooyin loogu talagalay tallaallada hargabka mRNA ma heli doonaan taageerada weyn ee dawladda ee tallaallada Covid-19 ay sameeyeen.Sidoo kale maamulayaashu uma oggolaan doonaan inay helaan oggolaansho degdeg ah.Hargabka xilliyeedka ma aha khatar cusub, waxaana mar hore lagaga hortagi karaa tallaallo shati leh.
Markaa soosaarayaashu waa inay qaadaan dariiqa dheer si ay u helaan oggolaan buuxda.Haddii tijaabooyinkii hore ee bukaan-socodka ay si fiican u soo baxaan, tallaal-bixiyeyaasha ayaa markaa u gudbi doona tijaabooyin ballaaran oo laga yaabo inay u baahdaan inay fidiyaan dhowr xilli oo hargab ah.
"Waa inay shaqeysaa," ayuu yiri Dr. Bartley oo ka tirsan Jaamacadda Connecticut."Laakin sida iska cad waa sababta aan cilmi baaris u sameyneyno - si aan u hubinno 'waa in' iyo 'wax la sameeyo' inay isku mid yihiin."
Waqtiga boostada: Abriil-21-2022